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Demodectic Mange (Demodicosis) is, as you obviously know, a type of follicular mites causing demodicosis. These are present, usually in small numbers, on many animal species including the dog and cat.
The life cycle of this spider mite is 18 - 24 days from the time the eggs are laid (usually deep in the hair follicle where the larvae develops) right to adulthood.
Puppies frequently contract this mite from their mother.
In the localized form, young dogs have one to several areas of hair loss, most commonly around the eyes and muzzle with erythema (rash) and scaling.
The generalized form includes the hair loss, scaling, rash, but often include pruritus (itching) and a secondary infection of bacteriologic origin. It should be checked for staphylococcal pyoderma as well.
Many canine forms will clear up on their own. Weekly use of parasite-dips, shampoos or lotions may help speed it up.
Prognosis for Generalized Demodicosis is not always promising (but costly). It may depend on the owner's cooperation in administering treatments offered and whether or not there's a genetic link.
In dogs under a year old, half will self-cure. Another factor that counts for resolution is the status of the immune system and other possible underlying conditions.
Immunosuppression associated with some neoplastic processes or disease such as (malignant) lymphosarcoma or melanoma, hyperadrenalcorticism, hypothyroidism, diabetes, Cushings Disease and so on must be ruled out as contributory.
Treatment with Mitaban@ (Amitraz) dip often works (FDA approves .025%; however, it has been administered in up to .125% in controlled veterinary environments, studies and trials). When treated without fail, as directed, mites should not appear in scrapings at 4 weeks after last treatment. It could take a few months to treat and scrapings should be done monthly.
Increasing concentration and frequency of Amitraz is generally done before administering oral options. Milbemycin Oxime or Ivermectin are popular Rx's (once a day x 60 to 90 days).
Again, secondary infections should be considered and also treated.
Since Juvenile onset Generalized Demodicosis is hereditary, neither sire nor dam of affected litters should ever be bred.
(References: Department of Diagnostic Medicine-Pathobiology, College of Veterinary Medicine, Kansas State University; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg; US Dept of Agriculture; others)
Many have forgotten this truth, but you must not forget it.
You remain responsible, forever, for what you have tamed.