Usually hot spots like this are started by flea bite allergies. These are usually made worse by biting, licking, or scratching. The important thing for successful treatment of a hot spot is to find the underlying cause to break the cycle of continued skin trauma and resulting inflammation. For many animals flea prevention such as Frontline can help do this.
I suggest cleaning the spots with Betadine (iodine solution) and they try neosporin or triple antibiotic ointment on the spots.
If you need to trim hair be very careful not to nick the skin as cat skin is very easy to slice - easer than mats may be.
You may need antibiotics from the vet to help cure this up.
You can read more here
http://netscape.petplace.com/articles/artShow.asp?artID=84
Hope this helps you!
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