Its time for a geriatric check up of your pet. The eyes sound like a serious eye infection is hurting her. The weight loss could be from pain or parasites or diseases of older dogs such as heart disease, liver problems, kidney disease or issues such as Cushings disease or diabetes.
You can read about Cushings here
www.marvistavet.com/html/cushing_s_disease.html
and diabetes here
www.marvistavet.com/html/diabetes_mellitus.html
The vet will do an exam and probably also need to do bloodwork.
Many of the problems older pets get are easily treated with inexpensive medications.
Hope this helps you!
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